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Assessing the effectiveness of Interleukin-2 therapy in experimental type 1 diabetes.

Zhengkang LuoMariela Mejia-CordovaNour HamzeElin BerggrenSaloni ChopraBilal SafiMartin BlixtStellan SandlerKailash Singh
Published in: Endocrine (2024)
In conclusion, further decreasing IL-2 dosage may not be a suitable approach for T1D therapy, and the limited success suggests that an alternative low dose IL-2 therapy strategy or other immunotherapies should be considered.
Keyphrases
  • type diabetes
  • low dose
  • randomized controlled trial
  • systematic review
  • high dose
  • metabolic syndrome
  • skeletal muscle
  • adipose tissue
  • mesenchymal stem cells
  • glycemic control
  • weight loss