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Blood-based microRNA profiling unveils complex molecular dynamics in breast cancer.

Mudassar ShahidRabbani SyedM A AnsariGowher ShafiJames John
Published in: Journal of applied genetics (2024)
This study provides significant insights into distinct miRNA expression patterns in normal and malignant breast tissues. The overlapping miRNA profiles in primary and malignant tumors underscore the complexity of genetic regulation in breast cancer. The identification of deregulated miRNAs and affected pathways contributes to our understanding of breast cancer pathogenesis. The validated miRNAs hold potential as diagnostic and prognostic markers, offering avenues for further clinical exploration in breast cancer research.
Keyphrases
  • molecular dynamics
  • poor prognosis
  • genome wide
  • dna methylation
  • young adults
  • binding protein