How does prescribing for antihypertensive products stack up against guideline recommendations? An Australian population-based study (2006-2014).
Andrea L SchafferSallie-Anne PearsonNicholas A BuckleyPublished in: British journal of clinical pharmacology (2016)
More than half of antihypertensive initiators conformed to Australian guidelines. Initiation on FDCs and other non-recommended treatments was associated with lower persistence on antihypertensive therapy in the first year. Long-term effectiveness and outcomes may be enhanced by initiating with low dose monotherapy.
Keyphrases
- blood pressure
- low dose
- hypertensive patients
- clinical practice
- primary care
- randomized controlled trial
- systematic review
- high dose
- open label
- type diabetes
- combination therapy
- clinical trial
- metabolic syndrome
- skeletal muscle
- adverse drug
- mesenchymal stem cells
- insulin resistance
- adipose tissue
- study protocol
- weight loss
- drug induced