Methods to Compare Adverse Events in Twitter to FAERS, Drug Information Databases, and Systematic Reviews: Proof of Concept with Adalimumab.
Karen SmithSu GolderAbeed SarkerYoon LokeKaren O'ConnorGraciela Gonzalez-HernandezPublished in: Drug safety (2019)
Social media posts often express mild and symptomatic ADRs, but rates are measured differently in scientific sources. ADRs in FAERS are reported as absolute numbers, in DIDs as percentages, and in systematic reviews as percentages, risk ratios, or other metrics, which makes comparisons challenging; however, overlap is substantial. Social media analysis facilitates open-ended investigation of patient perspectives and may reveal concepts (e.g. anxiety) not available in traditional sources.
Keyphrases
- social media
- health information
- systematic review
- drinking water
- meta analyses
- rheumatoid arthritis
- minimally invasive
- case report
- genome wide
- single cell
- emergency department
- randomized controlled trial
- big data
- sleep quality
- physical activity
- machine learning
- ulcerative colitis
- drug induced
- electronic health record
- data analysis