AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK.
Siegfried Karl WagnerFintan HughesMario Cortina-BorjaNikolas PontikosRobbert StruyvenXiaoxuan LiuHugh MontgomeryDaniel C AlexanderEric J TopolSteffen Erhard PetersenKonstantinos BalaskasJack HindleyAxel PetzoldJugnoo Sangeeta RahiAlastair K DennistonPearse Andrew KeanePublished in: BMJ open (2022)
AlzEye combines the world's largest single institution retinal imaging database with nationally collected systemic data to create an exceptional large-scale, enriched cohort that reflects the diversity of the population served. First analyses will address cardiovascular diseases and dementia, with a view to identifying hidden retinal signatures that may lead to earlier detection and risk management of these life-threatening conditions.
Keyphrases
- end stage renal disease
- high resolution
- optical coherence tomography
- cardiovascular disease
- diabetic retinopathy
- newly diagnosed
- ejection fraction
- chronic kidney disease
- cross sectional
- mild cognitive impairment
- prognostic factors
- emergency department
- peritoneal dialysis
- electronic health record
- type diabetes
- optic nerve
- big data
- adverse drug
- cardiovascular events
- high density