High-resolution Diffusion-weighted Imaging to Detect Changes in Tumor Size and ADC, and Predict Adverse Biopsy Histology during Prostate Cancer Active Surveillance.
Rola SaouafYibin XieSungjin KimYaniv RaphaelChristopher T NguyenDaniel J LuthringerTimothy John DaskivichEric M LoMourad TighiouartDebiao LiHyung Lae KimPublished in: Cancer research communications (2024)
We report on a prospective clinical trial using a MRI that has three times the resolution of standard MRI. During AS for prostate cancer, two high-resolution MRIs performed approximately a year apart can detect tumor changes that predict the presence of aggressive cancers that should be considered for curative therapy such as prostatectomy or radiation.
Keyphrases
- diffusion weighted imaging
- prostate cancer
- high resolution
- contrast enhanced
- magnetic resonance imaging
- clinical trial
- radical prostatectomy
- diffusion weighted
- mass spectrometry
- computed tomography
- magnetic resonance
- ultrasound guided
- radiation therapy
- open label
- emergency department
- randomized controlled trial
- tandem mass spectrometry
- study protocol
- phase ii
- bone marrow
- stem cells
- adverse drug
- young adults
- minimally invasive
- drug induced
- replacement therapy