Epidurals for Coarctation Repair in Children Are Associated with Decreased Postoperative Anti-Hypertensive Infusion Requirement as Measured by a Novel Parameter, the Anti-Hypertensive Dosing Index (ADI).
J Matthew KynesMatthew S ShotwellCamila B WaltersDavid P BichellJason T ChristensenStephen R HaysPublished in: Children (Basel, Switzerland) (2019)
This is the first study of children receiving an epidural for surgical repair of aortic coarctation via open thoracotomy. In this small, single-institution, observational retrospective cohort study, epidurals for coarctation repair in children were associated with decreased postoperative anti-hypertensive infusion requirements. Epidurals were not associated with length of ICU or hospital stay, or with discharge on anti-hypertensive medication. No significant epidural complications were noted. Prospective study of larger populations will be necessary to confirm these associations, address causality, verify safety, and assess other effects.
Keyphrases
- blood pressure
- young adults
- patients undergoing
- spinal cord
- healthcare
- adverse drug
- intensive care unit
- minimally invasive
- heart failure
- coronary artery disease
- aortic valve
- atrial fibrillation
- spinal cord injury
- pulmonary artery
- arterial hypertension
- cross sectional
- extracorporeal membrane oxygenation
- pulmonary arterial hypertension