Basolateral activation with TLR agonists induces polarized cytokine release and reduces barrier function in RPE in vitro.

Laura TerheydenJohann RoiderAlexa Klettner

Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2020)

Danger signals activating TLRs can induce polarized cytokine expression and contribute to the loss of barrier function in the RPE.

Keyphrases

poor prognosis
toll like receptor
inflammatory response
signaling pathway
immune response
binding protein
long non coding rna