Long noncoding RNAs (CTC-471J1.2, NeST) as epigenetic risk factors of active juvenile lupus nephritis: a case-control study.

Mohamed M ZedanAli SobhAlshimaa MagdyMai S KorkorZeinab R AttiaNada KhaledYousra SadeqAhmed Hazem El-NagdyAhmed E TahaMohamed Ahmed NoureldinMohamed TamanDoaa Mosad MosaMarwa H Elnagdy

Published in: Pediatric rheumatology online journal (2024)

The expression level of circulatory lncRNAs-CTC-471J1.2 and NeST can be used as sensitive and specific biomarkers for active LN. Furthermore, both could serve as predictors for nephritis activity.

Keyphrases

risk factors
circulating tumor cells
poor prognosis
dna methylation
circulating tumor
gene expression
binding protein
network analysis
transcription factor