Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Bryan A JohnsonYiyang ZhouKumari G LokugamageMichelle N VuNathen BoppPatricia A Crocquet-ValdesCraig SchindewolfYang LiuDionna SchartonJessica A PlanteXuping XiePatricia AguilarScott C WeaverPei-Yong ShiDavid H WalkerAndrew L RouthKenneth S PlanteVineet D MenacheryPublished in: bioRxiv : the preprint server for biology (2021)
A mutation in the nucleocapsid gene of the SARS-CoV-2 alpha variant is found to enhance replication, fitness, and pathogenesis.