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Prolonging the duration of post-infusion scalp cooling in the prevention of anthracycline-induced alopecia: a randomised trial in patients with breast cancer treated with adjuvant chemotherapy.

Manon M C KomenCorina J G van den HurkJohan W R NortierTjeerd van der PloegP NieboerJacobus J M van der HoevenCarolien H Smorenburg
Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2018)
Extending the duration of 90-min post-infusion scalp cooling to 150 min in patients treated with adjuvant FEC chemotherapy was well-tolerated but did not significantly diminish the need for head covering. However, grades 2-3 alopecia was seen less often with prolonged post-infusion scalp cooling.
Keyphrases
  • low dose
  • early stage
  • squamous cell carcinoma
  • study protocol
  • clinical trial
  • diabetic rats
  • randomized controlled trial
  • open label
  • radiation therapy
  • optic nerve