Prolonging the duration of post-infusion scalp cooling in the prevention of anthracycline-induced alopecia: a randomised trial in patients with breast cancer treated with adjuvant chemotherapy.
Manon M C KomenCorina J G van den HurkJohan W R NortierTjeerd van der PloegP NieboerJacobus J M van der HoevenCarolien H SmorenburgPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2018)
Extending the duration of 90-min post-infusion scalp cooling to 150 min in patients treated with adjuvant FEC chemotherapy was well-tolerated but did not significantly diminish the need for head covering. However, grades 2-3 alopecia was seen less often with prolonged post-infusion scalp cooling.