An Essential Role of c-Fos in Notch1-mediated Promotion of Proliferation of KSHV-Infected SH-SY5Y Cells.
Huiling XuJinghong HuangLixia YaoWenyi GuAynisahan RuziYufei DingYing LiWeihua LiangJinfang JiangZemin PanDongdong CaoNaiming ZhouDongmei LiJinli ZhangPublished in: Current molecular pharmacology (2024)
Our findings strongly indicate that c-Fos plays a crucial role in the promotion of cell proliferation through Notch1 signaling in KSHV-infected cells. Furthermore, our results suggest that the inhibition of expression of key viral pathogenic proteins is likely involved in this process.