Adjunctive cenobamate in people with focal onset seizures: Insights from the Italian Expanded Access Program.
Roberta RobertiGiovanni AssenzaFrancesca BisulliGiovanni BoeroCanafoglia LauraValentina ChiesaCarlo Di BonaventuraGiancarlo Di GennaroMaurizio EliaEdoardo FerlazzoAlfonso GiordanoAngela La NeveClaudio LiguoriStefano MelettiFrancesca Felicia OpertoNicola PietrafusaMonica PulighedduPatrizia PulitanoEleonora RosatiIlaria SammarraElena TartaraGiampaolo VattiFlavio Villaninull nullEmilio RussoSimona LattanziPublished in: Epilepsia (2024)
Adjunctive cenobamate was associated with a reduction in seizure frequency and in the burden of concomitant ASMs in adults with difficult-to-treat focal epilepsy. The type of ASM associated did not influence effectiveness except for a favorable trend with clobazam.