The expression of heparanase in term and preterm human placentas.

Amir NaehShay HantisteanuShilhav Meisel-SharonIlanit BoyangoMordechai HallakRinat Gabbay-Benziv

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

This study demonstrates for the first time that preterm vaginal deliveries are associated with higher expression of heparanase in placental tissue. This may imply a direct effect of heparanase on preterm labor. Further studies should evaluate the functional role by which heparanase influence preterm delivery.

Keyphrases

gestational age
low birth weight
preterm birth
preterm infants
poor prognosis
binding protein
long non coding rna
induced pluripotent stem cells