Prone positioning in non-intubated patients with COVID-19 associated acute respiratory failure, the PRO-CARF trial: A structured summary of a study protocol for a randomised controlled trial.

Miguel Á Ibarra-EstradaMiguel Marín-RosalesRoxana García-SalcidoSara A Aguirre-DíazAlexandra Vargas-ObietaQuetzalcóatl Chávez-PeñaJosé A López-PulgarínJulio C Mijangos-MéndezGuadalupe Aguirre-Avalos

Published in: Trials (2020)

The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. The study protocol has been reported in accordance with the Standard Protocol Items: Recommendations for Clinical Interventional Trials (SPIRIT) guidelines (Additional file 2).

Keyphrases

respiratory failure
randomized controlled trial
study protocol
extracorporeal membrane oxygenation
mechanical ventilation
clinical trial
clinical practice
liver failure
open label
phase iii
acute respiratory distress syndrome
intensive care unit
anti inflammatory
phase ii
drug induced
placebo controlled