Circulating LncRNAs landscape as potential biomarkers in breast cancer.

Zahra PourramezanFatemeh Akhavan AttarMaryam YusefpourMasoumeh AziziMana Oloomi

Published in: Cancer reports (Hoboken, N.J.) (2022)

In conclusion, the expression levels of circulating H19 and SPRY4-IT1 lncRNAs in breast cancer patients could consider as the prognostic biomarkers and therapeutic targets in breast cancer, because of their excellent power in discriminating breast cancer from healthy individuals and the significant correlation of H19, and SPRY4-IT1 lncRNAs with clinicopathological traits. We also suggest the possible application of BC040587 lncRNA as a diagnostic and prognostic indicator to assess tumor progression in case of verification in larger patients' cohorts.

Keyphrases

poor prognosis
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
long non coding rna
network analysis
peritoneal dialysis
prognostic factors
genome wide analysis
gene expression
genome wide identification
single cell
binding protein
young adults
long noncoding rna