Spatial Transcriptomic Analysis Using R-Based Computational Machine Learning Reveals the Genetic Profile of Yang or Yin Deficiency Syndrome in Chinese Medicine Theory.

Cheng ZhangChi Wing TamGuoyi TangYuanyuan ChenNing WangYibin Feng

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

Our study provides representative gene targets and modules for supporting clinical traits of Yang or Yin deficiency in Chinese medicine theory, which is beneficial for promoting the modernization of Chinese medicine theory. Besides, R-based machine learning approaches adopted in this study might be further applied for investigating the underlying genetic polymorphisms related to Chinese medicine theory.

Keyphrases

machine learning
genome wide
artificial intelligence
copy number
gene expression
replacement therapy
big data
cross sectional
network analysis