Blood-brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors.
Kevin BeccariaAria SabbaghJohn de GrootMichael CanneyAlexandre CarpentierAmy B HeimbergerPublished in: Journal of neuro-oncology (2020)
Ultrasound BBB opening has just recently entered clinical trials with encouraging results, and the association of this strategy with immune therapeutics creates a new field of brain tumor treatment.