Blood-brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors.

Kevin BeccariaAria SabbaghJohn de GrootMichael CanneyAlexandre CarpentierAmy B Heimberger

Published in: Journal of neuro-oncology (2020)

Ultrasound BBB opening has just recently entered clinical trials with encouraging results, and the association of this strategy with immune therapeutics creates a new field of brain tumor treatment.

Keyphrases

blood brain barrier
clinical trial
magnetic resonance imaging
cerebral ischemia
small molecule
computed tomography
randomized controlled trial
ultrasound guided
open label