The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort.
Rajat SuriDaniela MarkovicHan WooMehrdad ArjomandiR Graham BarrRussell P BowlerGerard CrinerJeffrey L CurtisMark T DransfieldM Bradley DrummondSpyridon FortisMeiLan K HanEirc A HoffmanRobert J KanerJoel Daniel KaufmanJerry A KrishnanFernando J MartinezJill OharVictor E OrtegaRobert Paine IiiXavier SolerPrescott G WoodruffNadia N HanselChristopher B CooperDonald P TashkinRussell G BuhrIgor Z BarjaktarevicPublished in: American journal of respiratory and critical care medicine (2024)
Chronic altitude exposure is associated with reduced functional exercise capacity in individuals with COPD, but this did not translate into differences in symptoms or health status. Additionally, chronic high-altitude exposure did not affect progression of disease as defined by longitudinal changes in spirometry.