VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9.

Laurence O W WilsonSara HetzelChristopher PockrandtKnut ReinertDenis Carolin Bauer

Published in: BMC biotechnology (2019)

VARSCOT allows researchers to take genomic variation into account when designing individual or population-wide targeting strategies. VARSCOT is available from https://github.com/BauerLab/VARSCOT .

Keyphrases

crispr cas
loop mediated isothermal amplification
genome editing
real time pcr
label free
cancer therapy
gene expression
dna methylation
quantum dots