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Knockdown of Fibromodulin Inhibits Proliferation and Migration of RPE Cell via the VEGFR2-AKT Pathway.

He HuShan-Shan LiJianqiao LiChao HuangFang ZhouLi ZhaoWenzhen YuXiao Qin
Published in: Journal of ophthalmology (2018)
Depletion of FMOD selectively downregulated the expression of VEGF and VEGFR2 and inhibited the signaling pathway of AKT phosphorylation, which consequently inhibited the proliferation and migration of RPE Cell.
Keyphrases
  • signaling pathway
  • vascular endothelial growth factor
  • single cell
  • cell therapy
  • cell proliferation
  • poor prognosis
  • pi k akt
  • epithelial mesenchymal transition
  • endothelial cells
  • induced apoptosis
  • long non coding rna