Clinical Characteristics and Risk Factors of First-Ever Stroke in Young Adults: A Multicenter, Prospective Cohort Study.
Yea Jin JoDae Hyun KimMin Kyun SohnJong Min LeeYong Il ShinGyung-Jae OhYang-Soo LeeMin Cheol JooSo Young LeeMin-Keun SongJunhee HanJeong Hoon AhnWon Hyuk ChangYun-Hee KimDeog Young KimPublished in: Journal of personalized medicine (2022)
Stroke in young adults has catastrophic consequences and has increased in prevalence, contrary to the trends of most other diseases. This study aimed to determine the major characteristics and risk factors for stroke in younger adults compared with older adults. From the Korean Stroke Cohort for Functioning and Rehabilitation, 10,584 patients with first-ever stroke between August 2012 and March 2015 were enrolled retrospectively and divided into younger (age ≤ 45) and older groups (age > 45). The clinical characteristics and risk factors of stroke were compared between the younger and older groups. The younger group comprised 915 patients (8.6%). The proportion of hemorrhage strokes in the younger group (42.3%) was significantly higher than in the older group (20.0%) ( p < 0.001). Obesity, current smoking, and heavy alcohol consumption were significantly more common risk factors in the younger group than in the older group for all stroke types, whereas hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, and coronary heart disease were significantly more frequent in the older group (both p < 0.001). The major risk factors in the younger group may be lifestyle-related. Therefore, increasing awareness of lifestyle-related risk factors may be necessary to prevent stroke in young adults.
Keyphrases
- atrial fibrillation
- risk factors
- young adults
- physical activity
- left atrial
- oral anticoagulants
- end stage renal disease
- metabolic syndrome
- catheter ablation
- middle aged
- left atrial appendage
- weight loss
- chronic kidney disease
- community dwelling
- insulin resistance
- blood pressure
- cardiovascular disease
- alcohol consumption
- heart failure
- type diabetes
- cerebral ischemia
- acute coronary syndrome
- cross sectional
- left ventricular
- peritoneal dialysis
- venous thromboembolism
- subarachnoid hemorrhage
- smoking cessation
- blood brain barrier
- mitral valve
- skeletal muscle