Rapid Synthesis of Luotonin A Derivatives via Synergistic Visible-Light Photoredox and Acid Catalysis.

Feng WuWuheng DongSijie FanYao YuanCaiyun LiangAiyu ChenZuodong YinZhao-Guo Zhang

Published in: The Journal of organic chemistry (2022)

The merging of visible-light photoredox and acid catalysis allowed for an intramolecular Povarov cycloaddition reaction using eosin Y as the photocatalyst and TsOH·H 2 O as the co-catalyst. A visible-light-promoted dehydrogenative cyclization protocol enabled the construction of Luotonin A derivatives with up to 97% yield.

Keyphrases

visible light
randomized controlled trial
structure activity relationship
cancer therapy
quantum dots
sensitive detection
metal organic framework