Review of the Application of Dual Drug Delivery Nanotheranostic Agents in the Diagnosis and Treatment of Liver Cancer.
Qinghe HanLianze DuLili ZhuDuo YuPublished in: Molecules (Basel, Switzerland) (2023)
Liver cancer has high incidence and mortality rates and its treatment generally requires the use of a combination treatment strategy. Therefore, the early detection and diagnosis of liver cancer is crucial to achieving the best treatment effect. In addition, it is imperative to explore multimodal combination therapy for liver cancer treatment and the synergistic effect of two liver cancer treatment drugs while preventing drug resistance and drug side effects to maximize the achievable therapeutic effect. Gold nanoparticles are used widely in applications related to optical imaging, CT imaging, MRI imaging, biomarkers, targeted drug therapy, etc., and serve as an advanced platform for integrated application in the nano-diagnosis and treatment of diseases. Dual-drug-delivery nano-diagnostic and therapeutic agents have drawn great interest in current times. Therefore, the present report aims to review the effectiveness of dual-drug-delivery nano-diagnostic and therapeutic agents in the field of anti-tumor therapy from the particular perspective of liver cancer diagnosis and treatment.
Keyphrases
- drug delivery
- high resolution
- gold nanoparticles
- cancer therapy
- randomized controlled trial
- magnetic resonance imaging
- computed tomography
- risk factors
- emergency department
- type diabetes
- stem cells
- combination therapy
- bone marrow
- magnetic resonance
- coronary artery disease
- high throughput
- replacement therapy
- mass spectrometry
- chronic pain
- adverse drug
- fluorescence imaging
- single cell
- high speed
- positron emission tomography
- reduced graphene oxide