Facile construction of dibenzodioxo[3.3.1]nonanes bearing spirocyclohexadienones via domino [4 + 2] cycloaddition/C(sp 3 )-H oxidative dehydrogenation coupling reactions.

Genhui ChenHongjiao LiGuojuan LiangQian PuLijuan BaiDexin ZhangYing YeYong LiJing Zhou Hui Zhou

Published in: Organic & biomolecular chemistry (2022)

A novel palladium catalyzed homodimerization of ortho -hydroxyphenyl substituted p -QMs has been developed via [4 + 2] cycloaddition/oxidative dehydrogenation coupling domino reactions. An interesting palladium catalyzed intramolecular benzyl C-H oxidation dehydrogenation to form a transannular C(sp 3 )-O bond was found. This protocol provided an efficient method to construct various dibenzodioxo[3.3.1]nonanes bearing spirocyclohexadienones.

Keyphrases

electron transfer
room temperature
randomized controlled trial
molecular docking
hydrogen peroxide
visible light
reduced graphene oxide
energy transfer
metal organic framework
gold nanoparticles