Fertility-Sparing Approach in Patients with Endometrioid Endometrial Cancer Grade 2 Stage IA (FIGO): A Qualitative Systematic Review.

Pierluigi GiampaolinoValeria CafassoDominga BocciaMario AscioneAntonio MercorioFrancesco ViciglioneMario PalumboPaolo SerafinoCira BuonfantinoMaria Chiara De AngelisPaolo VerrazzoGiovanna GrassoGiuseppe GulloGiuseppe BifulcoLuigi Della Corte

Published in: BioMed research international (2022)

The conservative treatment may be an option for patients with stage IA G2 EEC who desire to preserve their fertility. The immunohistochemical markers evaluation looks promising in predicting response to conservative treatment. Further large series and randomized clinical trials are needed to confirm these results.

Keyphrases

endometrial cancer
systematic review
meta analyses
randomized controlled trial
clinical trial
combination therapy
clinical evaluation