Long non-coding RNA LINC00858 aggravates the oncogenic phenotypes of ovarian cancer cells through miR-134-5p/RAD18 signaling.

Heng XueZhihui WuDongdong RaoBimin ZhuoQingquan Chen

Published in: Archives of gynecology and obstetrics (2020)

LINC00858 sequestered miR-134-5p to elevate RAD18 expression, resulting in aggravated development of ovarian cancer. This might provide promising targets for treating patients with ovarian cancer.

Keyphrases

long non coding rna
poor prognosis
dna repair
dna damage
transcription factor
oxidative stress