A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: the UPSIDE study protocol.

Julia SpieringsAnna van RhenenPaco Mw WelsingAnne Ca MarijnissenEllen De LangheNicoletta Del PapaDaan DierickxKarina R GheorgheJoerg HenesRoger HesselstrandTessa KerrePer LjungmanArjan A van de LoosdrechtErik Waf MarijtMiro MayerMarc SchmalzingRoland SchroersVanessa SmithReinhard E VollMadelon C VonkAlexandre E VoskuylJeska K de Vries-BouwstraUlrich A WalkerDirk M WuttgeJacob M van Laar

Published in: BMJ open (2021)

NCT04464434; NL 8720.

Keyphrases

study protocol
systemic sclerosis
open label
clinical trial
phase iii
phase ii
interstitial lung disease
randomized controlled trial
phase ii study
double blind
placebo controlled
low grade
squamous cell carcinoma
rheumatoid arthritis
radiation therapy
rectal cancer