Evolution from a first clinical demyelinating event to multiple sclerosis in the REFLEX trial: Regional susceptibility in the conversion to multiple sclerosis at disease onset and its amenability to subcutaneous interferon beta-1a.
Marco BattagliniHugo VrenkenRiccardo Tappa BrocciGiordano GentileLudovico LuchettiAdriaan VersteegMark S FreedmanBernard M J UitdehaagLudwig KapposGiancarlo ComiAndrea SeitzingerDominic JackMaria Pia SormaniFrederik BarkhofNicola De StefanoPublished in: European journal of neurology (2022)
T2 lesion distribution in specific brain locations predict conversion to McDonald MS and show significantly reduced new lesion occurrence after treatment with sc IFN β-1a in an FCDE population.