Genetic variants associated with metabolic dysfunction-associated fatty liver disease in western China.

Shenling LiaoKang AnZhi LiuHe HeZhen-Mei AnQiaoli SuShuangqing Li

Published in: Journal of clinical laboratory analysis (2022)

In the Han population in western China, no association was found between these SNPs and the risk of MAFLD. PNPLA3 rs738409 was associated with aspartate aminotransferase levels in MAFLD patients. GCKR variants were associated with increased triglyceride levels and reduced serum fasting glucose in patients with MAFLD.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
south africa
blood glucose
newly diagnosed
peritoneal dialysis
oxidative stress
copy number
type diabetes
patient reported outcomes
genome wide
gene expression
adipose tissue
fatty acid