Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failure.
Yunyun WangFengtian WuChao ChenLichen XuWei LinChunhong HuangYing YangShanshan WuJinjin QiHanqin CaoGuojun LiMeng HongHaihong ZhuPublished in: BMC gastroenterology (2021)
suPAR was a useful independent biomarker of short-term outcomes in patients with ACLF and might play a key role in the pathogenesis. Trial registration CNT, NCT02965560.
Keyphrases
- liver failure
- reactive oxygen species
- hepatitis b virus
- phase iii
- study protocol
- cardiovascular events
- clinical trial
- phase ii
- risk factors
- randomized controlled trial
- coronary artery disease
- drug induced
- cardiovascular disease
- open label
- binding protein
- intensive care unit
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation