Inhibition of epidermal growth factor receptor suppresses parathyroid hormone-related protein expression in tumours and ameliorates cancer-associated cachexia.
Bahar Zehra Camurdanoglu WeberSamet AgcaAylin DomanikuSevval Nur BilgicDilsad H ArabaciSerkan KirPublished in: Journal of cachexia, sarcopenia and muscle (2022)
Epidermal growth factor receptor signalling regulates expression of cachexia mediator PTHrP. EGFR inhibition reduces PTHrP expression in LLC tumours and ameliorates cachexia in LLC tumour-bearing mice.