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Polygenic risk for traumatic loss-related PTSD in US military veterans: Protective effect of secure attachment style.

Ruth H AschIrina EsterlisFrank R WendtLorig KachadourianSteven M SouthwickJoel GelernterRenato PolimantiRobert H Pietrzak
Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)
Having a secure attachment style may help mitigate polygenic risk for developing traumatic loss-related PTSD in US veterans. Podosomes, which are implicated in inflammatory and neuroplasticity processes, may contribute to the genetic liability to developing loss-related PTSD. Psychological treatments targeting attachment security may help mitigate increased polygenic risk for loss-related PTSD in this population.
Keyphrases
  • posttraumatic stress disorder
  • spinal cord injury
  • social support
  • gene expression
  • public health
  • dna methylation
  • drug delivery
  • physical activity
  • cancer therapy
  • breast cancer risk