Pathological significance and prognostic role of LATS2 in prostate cancer.

Tsuyoshi MatsudaYasuyoshi MiyataYuichiro NakamuraAsato OtsuboYuta MukaeJunki HaradaKensuke MitsunariTomohiro MatsuoKojiro OhbaBungo FurusatoHideki Sakai

Published in: The Prostate (2021)

LATS2 acts as a tumor suppressor in PC. LATS2 expression is a useful predictor for BCR. LATS2-related activities are possibly dependent on the androgen-dependency of PC cells. Therefore, we suggest that LATS2 could be a potential therapeutic target and a useful predictor for outcome in patients with PC.

Keyphrases

prostate cancer
poor prognosis
radical prostatectomy
tyrosine kinase
risk assessment
climate change
long non coding rna
chronic myeloid leukemia
drug induced