TIPE3 hypermethylation correlates with worse prognosis and promotes tumor progression in nasopharyngeal carcinoma.

Xian-Yue RenXin WenYing-Qing LiJian ZhangQing-Mei HeXiao-Jing YangXin-Ran TangYa-Qin WangPan-Pan ZhangXiao-Zhong ChenBin ChengJun MaNa Liu

Published in: Journal of experimental & clinical cancer research : CR (2018)

TIPE3 downregulation correlates with its CGI hypermethylation in several solid cancers. TIPE3 acts as a tumor suppressor in NPC, providing a further insight into NPC progression and representing a potential prognostic biomarker for NPC.

Keyphrases

poor prognosis
cell proliferation
signaling pathway