Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review.

Fulvio CelsiFrancesca PeriJulia CavasinLuisa Zupin Giorgio CozziEgidio BarbiSergio Crovella

Published in: Genes (2023)

Despite the high variability observed in the different studies analyzed, our results suggest that hypermethylation and increased pain sensitivity could be connected, possibly due to the variation of TRPA1 expression.

Keyphrases

chronic pain
poor prognosis
pain management
binding protein
genome wide
dna methylation
case control
long non coding rna
human health
climate change
brain injury
neuropathic pain
blood brain barrier