Login / Signup

Epigenetic modulation of FOXM1-gene interacting network by BET inhibitors in breast cancer.

Javier Pérez-PeñaBalázs GyőrffyEitan AmirAtanasio PandiellaAlberto Ocaña
Published in: Breast cancer research and treatment (2018)
Our study demonstrates that activation of the FOXM1 pathway has a prognostic role in breast cancer. JQ1 can modulate the expression of the FOXM1-gene interacting network, opening the opportunity for the evaluation of this compound in breast cancer patients.
Keyphrases
  • genome wide
  • copy number
  • poor prognosis
  • dna methylation
  • genome wide identification
  • protein kinase
  • gene expression
  • binding protein
  • transcription factor
  • long non coding rna
  • network analysis