The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy.
Zheng-Quan DongZhou MaMeiju YangLinlin CongRuipeng ZhaoLiyun ChengJian SunYunfei WangRuijia YangXiaochun WeiPengcui LiPublished in: Journal of inflammation research (2022)
Based on the results above, we concluded that HDAC4 expression regulates the onset and development of age-related OA by controlling chondrocyte hypertrophy. These results may help in the development of early diagnosis and treatment of age-related OA.