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Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens.

Hyeri SeokJae-Hoon KoKyong-Ran PeckJi-Yeon KimJi Hye LeeGa Eun ParkSun Young ChoCheol-In KangNam Yong LeeDoo Ryeon Chung
Published in: Pneumonia (Nathan Qld.) (2019)
Combination antibiotic regimens were not associated with a survival benefit over β-lactam monotherapy in the treatment of community-onset neutropenic pneumonia. Unnecessary combination therapy should be reconsidered in cancer patients who are at high risk for adverse drug reactions and colonization with multi-drug resistant organisms.
Keyphrases
  • combination therapy
  • drug resistant
  • adverse drug
  • multidrug resistant
  • healthcare
  • mental health
  • gram negative
  • acinetobacter baumannii
  • randomized controlled trial
  • cystic fibrosis
  • pseudomonas aeruginosa