Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens.
Hyeri SeokJae-Hoon KoKyong-Ran PeckJi-Yeon KimJi Hye LeeGa Eun ParkSun Young ChoCheol-In KangNam Yong LeeDoo Ryeon ChungPublished in: Pneumonia (Nathan Qld.) (2019)
Combination antibiotic regimens were not associated with a survival benefit over β-lactam monotherapy in the treatment of community-onset neutropenic pneumonia. Unnecessary combination therapy should be reconsidered in cancer patients who are at high risk for adverse drug reactions and colonization with multi-drug resistant organisms.