The MTHFR promoter hypermethylation pattern associated with the A1298C polymorphism influences lipid parameters and glycemic control in diabetic patients.
Herlanny Santana BezerraCaroline Severo de AssisMayara Karla Dos Santos NunesIsabella Wanderley de Queiroga EvangelistaJoão M FilhoCecília Neta Alves Pegado GomesRayner Anderson Ferreira do NascimentoRafaella Cristhine Pordeus LunaMaria José de Carvalho CostaNaila Francis Paulo de OliveiraDarlene Camati PersuhnPublished in: Diabetology & metabolic syndrome (2019)
The hypermethylated methylation profile associated with the 1298AA genotype appeared to be connected to higher values of glycemia, total cholesterol and LDL cholesterol.