Preventing Brain Damage from Hypoxic-Ischemic Encephalopathy in Neonates: Update on Mesenchymal Stromal Cells and Umbilical Cord Blood Cells.

Makoto NabetaniTakeo MukaiHaruo Shintaku

Published in: American journal of perinatology (2021)

· This study includes new insights about cell therapy for neonatal HIE and CP in schema.. · This study shows precise mechanism of neonatal HIE cascade.. · The mechanism of cell therapy by comparing umbilical cord blood stem cell with MSC is shown.. · The review of recent clinical trials of UC-MSC is shown..

Keyphrases

umbilical cord
cell therapy
mesenchymal stem cells
stem cells
clinical trial
bone marrow
induced apoptosis
early onset
randomized controlled trial
low birth weight
signaling pathway
endoplasmic reticulum stress
phase ii
double blind