Elevated ZBTB7A expression in the tumor invasive front correlates with more tumor budding formation in gastric adenocarcinoma.
Yujing SunJunyi HeDuan-Bo ShiHui ZhangXu ChenAi-Yan XingPeng GaoPublished in: Journal of cancer research and clinical oncology (2020)
Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway.