Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer.

Shouping XuPeiyuan WangJian ZhangHao WuShiyao SuiJinfeng ZhangQin WangKun QiaoWeiwei YangHongbiao XuDa Pang

Published in: Molecular cancer (2019)

These findings broaden comprehensive understanding of the biology function of Ai-lncRNAs. Proper regulation of EGOT may be a novel synergistic strategy for enhancing paclitaxel sensitivity in cancer therapy.

Keyphrases

cancer therapy
poor prognosis
artificial intelligence
endothelial cells
drug delivery
long non coding rna
nucleic acid
papillary thyroid
binding protein
cell death
oxidative stress
cell proliferation
endoplasmic reticulum stress
machine learning
induced apoptosis
small molecule
amino acid