Obesity, Inflammation, and Clinical Outcomes in COVID-19: A Multicenter Prospective Cohort Study.
Christina G HuttenKishan PadaliaAlexi VasbinderYiyuan HuangAnis IsmailIan PizzoKristen Machado DiazTonimarie CatalanFeriel PresswallaElizabeth AndersonGrace ErneBrayden BittermanPennelope BlakelyEvangelos J Giamarellos-BourboulisSven H LoosenFrank TackeAthanasios ChalkiasJochen ReiserJesper Eugen-OlsenMousumi BanerjeePradipta R RaySalim Salim HayekPublished in: The Journal of clinical endocrinology and metabolism (2024)
Obesity is associated with worse outcomes in COVID-19, notably in younger participants and in the pre-Omicron era. Inflammation, as measured by suPAR, is a significant mediator of the association between obesity and COVID-19 outcomes.