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Inflammatory markers, somatic complaints, use of medication and health care in 11-year-old children at familial high risk of schizophrenia or bipolar disorder compared with population-based controls. The Danish High Risk and Resilience Study - via 11.

Anne SøndergaardMaja GregersenMartin WilmsJulie Marie BrandtCarsten HjorthøjJessica OhlandSinnika Birkehøj RohdNicoline HemagerAnna Krogh AndreassenChristina Bruun KnudsenLotte VeddumMette Falkenberg KrantzAja GreveVibeke BlikstedOle MorsKasper LykkegaardPeter KrustrupAnne E ThorupMerete Nordentoft
Published in: Nordic journal of psychiatry (2024)
Children at FHR-SZ had higher concentrations of leucocytes and neutrophilocytes than PBC. Children at FHR-SZ or FHR-BP displayed more somatic complaints than controls. Our study highlights rarely explored disadvantage of being born to parents with schizophrenia or bipolar disorder. To enhance understanding of how physical conditions in childhood may interplay with later transition to mental disorders in children at FHR-SZ and FHR-BD, further research is needed.
Keyphrases
  • bipolar disorder
  • major depressive disorder
  • healthcare
  • young adults
  • mental health
  • physical activity
  • emergency department
  • climate change
  • early onset
  • depressive symptoms
  • social support
  • early life