The Cost-Effectiveness of Adapting and Implementing a Brief Intervention to Target Frequent Alcohol Use Among Persons with HIV in Vietnam.
Natalie A BlackburnVivian F GoQuynh BuiHeidi HuttonRadhika P TampiTeerada SripaipanTran Viet HaCarl A LatkinShelley GoldenCarol GolinGeetanjali ChanderConstantine FrangakisNisha GottfredsonDavid W DowdyPublished in: AIDS and behavior (2021)
Brief interventions to reduce frequent alcohol use among persons with HIV (PWH) are evidence-based, but resource-constrained settings must contend with competition for health resources. We evaluated the cost-effectiveness of two intervention arms compared to the standard of care (SOC) in a three-arm randomized control trial targeting frequent alcohol use in PWH through increasing the percent days abstinent from alcohol and viral suppression. We estimated incremental cost per quality-adjusted life year (QALY) gained from a modified societal perspective and a 1-year time horizon using a Markov model of health outcomes. The two-session brief intervention (BI), relative to the six-session combined intervention (CoI), was more effective and less costly; the estimated incremental cost-effectiveness of the BI relative to the SOC, was $525 per QALY gained. The BI may be cost-effective for the HIV treatment setting; the health utility gained from viral suppression requires further exploration.
Keyphrases
- randomized controlled trial
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- healthcare
- hepatitis c virus
- hiv aids
- public health
- men who have sex with men
- sars cov
- quality improvement
- mental health
- high intensity
- physical activity
- palliative care
- south africa
- clinical trial
- phase iii
- risk assessment
- chronic pain
- drug delivery
- phase ii
- social media
- placebo controlled
- affordable care act