Human pancreatic α- to β-cell area ratio increases after type 2 diabetes onset.
Yukari FujitaJunji KozawaHiromi IwahashiSho YonedaSae UnoHidetoshi EguchiHiroaki NaganoAkihisa ImagawaIichiro ShimomuraPublished in: Journal of diabetes investigation (2018)
The pancreatic α/β increases after type 2 diabetes onset and correlates with diabetes duration. This change might occur through α-cell proliferation and phenotypic changes in pancreatic endocrine cells.