The Lessebo Effect in Disease Modification Trials in Parkinson's Disease.
Tiago A MestreMichael P McDermottRaquel LoboJoaquim José FerreiraAnthony E LangPublished in: Movement disorders : official journal of the Movement Disorder Society (2023)
We did not observe the lessebo effect in DMT. The necessary use of a placebo (and no active comparator) is a limitation. The prospective measurement of expectation of benefit could help to evaluate the many impacts of placebo use. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.