Refining Prognosis in Localized Gastrointestinal Stromal Tumor: Clinical Significance of Phosphatase and Tensin Homolog Low Expression and Gene Loss.

Xiaolan FengHaocheng LiJoanna FourquetMehdi BrahmiArmelle DufresneAlexandra MeurgeyIsabelle L Ray-Coquard Qing Wang Julien Bollard Francoise DucimetiereFrederic ChibonJean Yves Blay

Published in: JCO precision oncology (2022)

PTEN low expression/gene loss is an independent significant prognostic factor and a promising component to strengthen the clinical prognostic tools in patients with localized GIST.

Keyphrases

prognostic factors
poor prognosis
genome wide
copy number
binding protein
cell proliferation
genome wide identification
gene expression
transcription factor