The Application of Molecular Techniques for Assessment of SOX2 and miR126 Expression as Prognostic Markers in Esophageal Carcinoma.

Amal F GharibWael H ElsawyAmani A AlrehailiHanan S AminHayaa M AlhuthaliMaha M BakhuraysahAhmad A El Askary

Published in: Computational and mathematical methods in medicine (2022)

In esophageal cancer, SOX2 works as an oncogene, whereas miR-126 acts as a tumor suppressor gene. SOX2 overexpression and miR-126 downregulation were shown to be linked to a poor prognosis.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
transcription factor
stem cells
long noncoding rna
signaling pathway
copy number
gene expression